Green Coffee Bean Extract: Chlorogenic acid is a natural compound found in raw green coffee
beans. When coffee beans are roasted, the chlorogenic acid is mostly destroyed, so any weight
loss benefit from drinking regular coffee (i.e. coffee brewed from roasted coffee beans) would be
mostly non-existent. Chlorogenic acid has been specifically shown to inhibit an enzyme, glucose6-phosphatase, which promotes the formation of glucose (sugar) in the liver. Hence, chlorogenic
acid in coffee may be responsible, at least in part, for the reduced risk of glycemic disorders, such
as diabetes. Chlorogenic acid inhibits the release of glucose into the blood stream, by slowing down
the absorption of glucose in the blood stream. The chlorogenic acid ultimately results in a reduction
in the absorption of fat. Various studies have shown that chlorogenic acid slows absorption of fat
from food intake and also activates metabolism of extra fat. Unfortunately, traditional brewed coffee
doesn’t serve as a good source of chlorogenic acid. Roasting green coffee beans removes its
naturally bitter taste, but also removes a significant portion of chlorogenic acid. Hence, green coffee
beans remain one of the best natural sources. In a study on green coffee bean, published in the
Diabetes, Metabolic Syndrome and Obesity Journal, researchers followed a group of 16 adults who
supplemented with a special green coffee bean extract of chlorogenic acids at different dosages
(either 700 or 1050 milligrams per day) for 12 weeks. All 16 adults were considered overweight,
as demonstrated by a BMI of greater than 25 (a normal BMI is between 18.5 and 25). The extract
the researchers used contained an ingredient called GCA, which contains a standard green coffee
extract of total chlorogenic acids and other hydroxycinnamic acids that have been known to have
antioxidant health benefits. The subjects lost an average of 8kg. This was 10% of their overall body
weight and 4.4% of their overall body fat. Recent chlorogenic acid research was discussed by Dr.
Vinson in a presentation at the 245th National Meeting & Exposition of the American Chemical Society
(ACS), the world’s largest scientific society. Vinson discussed the potential of natural substances
extracted from unroasted coffee beans to help control the elevated blood sugar levels and body
weight which underpin type 2 diabetes. His presentation focused on chlorogenic acids. He pointed
out that type 2 diabetes, the most common form of diabetes, is an increasing global health problem,
with almost 26 million patients in the United States alone. Vinson said, “A simple natural pill or
capsule that would both help control blood sugar and foster weight loss at the same time, would
be a major advance in the treatment of type 2 diabetes,” He added, “Our own research and studies
published by other scientists suggest that such a treatment may, indeed, exist. There is significant
epidemiological and other evidence that coffee consumption reduces the risk of type 2 diabetes.”
Vinson said “One large study indicated a 50 percent risk reduction for people who drank seven cups
of coffee a day compared to those who drank only two cups a day. I am trying to make the coffee
and diabetes story as clear as possible for the public. The evidence points to chlorogenic acids as
the active ingredients in coffee that both prevent diabetes and improve glucose control in normal,
pre-diabetic and diabetic people.”


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