Dr Boxall’s – Sceletium Griffonia Vitamin B6 3 In 1 60’s

Sceletium Tortuosum is revered for its mood-enhancing effect, increasing alertness
which gently fades into calmness, offering relief from tension, stress and anxiety. The moodelevating action of Sceletium is caused by a number of alkaloids including mesembrine,
mesembrenol and tortuosamine. These interact with the brain’s dopamine and serotonin
receptors, also known as neurotransmitters, as a potent serotonin-uptake inhibitor. As a
serotonin–uptake inhibitor, the brain is made proficient in reclaiming neurotransmitters from
the neuron receptors to the originating nerves, thus keeping more serotonin in circulation.
Sceletium is known to have a balancing effect on other feel-good neurotransmitters like
dopamine, norepinephrine, and on adrenaline. Thus, mesembrine allows the brain to function
with reduced levels of serotonin, allowing time for natural levels to build up. Sceletium is
non- addictive, non hallucinogenic, and no severe adverse effects have been documented.
Griffonia Seed Extract (5HTP) is a natural supplement which contains the extract of the
Griffonia simplicifolia plant. Normally, serotonin is made from tryptophan that is found in the
foods that we eat. However, individuals suffering from anxiety, depression, insomnia and
other mood disorders are often found to have low levels of serotonin. While supplementing
with tryptophan can be moderately effective, it is even better to use 5-Hydroxytryptophan
(5-HTP) which is converted to serotonin at a faster rate than tryptophan itself. 5-HTP is an
intermediary in the production of serotonin so it gets you one step closer to the end product,
while avoiding some of the rate-limiting factors that regulate how much tryptophan is taken
up by the brain. Griffonia is one of a small number of natural sources for 5-HTP, which is
why this supplement has become so popular. Griffonia seed extract is metabolized by the
liver where the active ingredient 5-HTP can then enter the blood stream. Once it reaches the
brain, it readily crosses the blood-brain-barrier to enter the nervous system. It is here that it
can be converted into Serotonin and bind to receptors on your neurons.
Vitamin B6: These effects of 5-HTP can be further enhanced if you compliment it with
Vitamin B6. The B-vitamins are famously connected to improving mood, controlling anxiety,
enhancing focus and even boosting memory. Vitamin B6 in particular (also known as
pyridoxine) is involved in making the neurotransmitters serotonin and norepinephrine in the
brain. This vitamin also helps to protect brain cells by maintaining the layer known as the
myelin sheath that surrounds your neurons. Taking vitamin B6 in conjunction with 5-HTP can
boost its stress relief effects and help to promote feelings of happiness, mental clarity and
contentment.